5' nucleases derived from thermostable DNA polymerase

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United States of America Patent

PATENT NO 5614402
SERIAL NO

08254359

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Abstract

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A means cleaving a nucleic acid cleavage structure in a site-specific manner is disclosed. A cleaving enzyme having 5' nuclease activity without interfering nucleic acid synthetic ability is employed as the basis of a novel method of detection of specific nucleic acid sequences.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATEDATTN PATENT DEPT 10210 GENETIC CENTER DRIVE SAN DIEGO CA 92121
BIOLUCENT LLC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC CORPORATION250 CAMPUS DRIVE MARLBOROUGH MA 01752
HOLOGIC INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
SUROS SURGICAL SYSTEMS INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
THIRD WAVE TECHNOLOGIES INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP250 CAMPUS DRIVE MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brow, Mary Ann D Madison, WI 56 3935
Dahlberg, James E Madison, WI 44 2304
Lyamichev, Victor I Madison, WI 62 3805

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