Method of treating atherosclerosis or restenosis using microtubule stabilizing agent

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United States of America Patent

PATENT NO 5616608
SERIAL NO

08633185

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is a method of preventing or reducing atherosclerosis or restenosis, and a pharmaceutical preparation used therefor. In particular, it is a method of preventing or reducing atherosclerosis or restenosis after arterial injury by treatment with a low dose of a microtubule stabilizing agent such as taxol or a water soluble taxol derivative. The low dose used in the present invention prevents artery blockage while minimizing any negative side effects associated with the drug.

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Patent Owner(s)

  • NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinsella, James L Baltimore, MD 12 457
Sollott, Steven J Baltimore, MD 10 292

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