Hypersensitive constriction velocity method for diagnosing Alzheimer's disease in a living human
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United States of America Patent
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Apr 8, 1997
Issued Date -
N/A
app pub date -
May 23, 1995
filing date -
Jul 25, 1994
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Abstract
The present invention provides a non-invasive method for diagnosing Alzheimer's disease in a living human subject. The diagnostic method employs a non-invasive automated apparatus which can repetitively measure pupil constriction velocity for a pre-chosen duration both before and after stimulation by visible light; and cumulatively record such measured pupil constriction velocity data as is obtained over time. The method also administers at least one neural transmitter mediator to a targeted eye of the living subject in an amount insufficient to cause marked changes in pupillary dynamic response in a person who is not afflicted with Alzheimer's disease. The marked hypersensitivity of an Alzheimer's dementia patient to the administered neural transmitter mediator causes a marked change in pupil constriction velocity and thus serves as the means diagnostically to determine and identify an individual living human subject as being afflicted with Alzheimer's disease.
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