Modular assembly of antibody genes, antibodies prepared thereby and use

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United States of America Patent

PATENT NO 5618920
SERIAL NO

08235225

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Abstract

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The invention relates to the secretion of heavy chain immunoglobulin fragments and light chain immunoglobulins from prokaryotic hosts using a prokaryotic secretion signal peptide wherein the heavy chain fragments and light chains are capable of associating to form an antigen binding antibody fragment.

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Patent Owner(s)

Patent OwnerAddress
XOMA TECHNOLOGY LTD2 CHURCH STREET CLARENDON HOUSE HAMILTON HM11

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Better, Marc Los Angeles, CA 12 1080
Horwitz, Arnold H Los Angeles, CA 27 1224
Lei, Shau-Ping Los Angeles, CA 16 1304
Liu, Alvin Y Oceanside, CA 17 2264
Robinson, Randy R Los Angeles, CA 22 2541
Wall, Randolph Sherman Oaks, CA 8 977
Wilcox, Gary L Malibu, CA 10 1073

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