Liposomes for treatment of B-cell and T-cell disorders

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United States of America Patent

PATENT NO 5620689
SERIAL NO

08475050

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of treating a subject having a disorder characterized by a neoplasm of B-lymphocyte or T-lymphocyte lineage cells is described. The method includes administering a suspension of liposomes having a surface coating of polyethylene glycol chains. Attached to the distal ends of the chains are antibodies or antibody fragments effective to bind to an antigen specific to the affected cells. In one embodiment, anti-CD19 antibodies are attached to the liposome-bound chains, for treatment of multiple myeloma.

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Patent Owner(s)

Patent OwnerAddress
SEQUUS PHARMACEUTICALS INC A DE CORP960 HAMILTON COURT MENLO PARK CA 94025

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Theresa M Edmonton, CA 21 1707
Martin, Francis J San Francisco, CA 78 5146

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