Use of metabotropic receptor agonists in progressive neurodegenerative diseases

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United States of America Patent

PATENT NO 5622981
SERIAL NO

08418903

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Abstract

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A method of treating a mammal with a neurodegenerative disease which is caused at least in part by the neurotoxic effects of the .beta.-amyloid protein. This method constitutes administering a metabotropic receptor agonist to such a mammal. In particular, the agonist trans-ACPD or 1S,3R-ACPD can be administered intravenously to treat a mammal with Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
CORTEX PHARMACEUTICALS INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cotman, Carl W Santa Ana, CA 12 120
Eveleth, David D Mission Viejo, CA 3 130
Kelleher, Judith A Irvine, CA 15 161

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