Macrocyclic antibiotics as separation agents
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United States of America Patent
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May 6, 1997
Grant Date -
N/A
app pub date -
Sep 29, 1995
filing date -
Feb 22, 1994
priority date (Note) -
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Abstract
Macrocyclic antibiotics having ring structures with at least 10 members act as separation agents in crystallization, precipitation, filtration, electrophoresis and chromatography. The macrocyclic antibiotics include ansamacrolides, macrolides, macrocyclic peptides, polyenes and derivatives thereof. The process has been found to be especially advantageous for separation of optical isomers by electrophoresis and chromatography.
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