Endotoxin binding and neutralizing protein and uses thereof
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United States of America Patent
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May 6, 1997
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jun 23, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Endotoxin binding/neutralizing proteins capable of binding endotoxin in vivo, thereby neutralizing the toxic effect or bioactivity of endotoxin which are isolated from a horseshoe crab such as Limulus polyphemus, pharmaceutical compositions and pharmaceutical uses of the proteins, a method of purifying the proteins and an assay for endotoxin based on the proteins, are disclosed.
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