Process for disintegrating cell dispersions or cell suspensions by means of ultrasonication for the purpose of isolating cell constituents
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United States of America Patent
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May 13, 1997
Grant Date -
N/A
app pub date -
Aug 1, 1994
filing date -
Dec 7, 1992
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Abstract
A process capable of being continuously carried out, for disintegrating cell material in the form of dispersions or suspensions in water for the purpose of obtaining cell constituent. Selected parameters permit avoidance of use of solid ultrasonication activators and the establishment of a particular geometry form for the acoustic irradiation container. The parameters include sonotrode immersion angle, length of immersion, ratio of extent of immersion of the sonotrode relative to the acoustic irradiation volume and the ratio of extent of immersion to the solid matter content of the medium to be sonicated.
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