Method for making freeze dried drug dosage forms
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United States of America Patent
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May 20, 1997
Grant Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jul 9, 1993
priority date (Note) -
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Abstract
The present invention discloses an improved technique for preparing a rapidly dispersing pharmaceutic tablet of a granular therapeutic agent which has both relatively low solubility and relatively large particle size. Xanthan gum is added to a liquid admixture of solvent, carrier components, and the granular therapeutic agent. The xanthan gum not only facilitates suspension of the granular therapeutic agent in the liquid admixture, but, more surprisingly, does so without adversely effecting the dispersion qualities and texture of the tablet in the patient's mouth upon administration.
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