Looped, hairpin ribozyme
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United States of America Patent
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May 20, 1997
Grant Date -
N/A
app pub date -
Dec 29, 1994
filing date -
Jul 2, 1992
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A polyribonucleotide having a thermodynamically stable loop structure and ribozyme activity and a DNA that codes for the polyribonucleotide. The polyribonucleotide has the following structure ##STR1## Direct administration of the ribozyme polyribonucleotide of the present invention into the body of a patient enables a target polyribonucleotide in the body to be efficiently cleaved, thereby allowing it to be used as an anti-AIDS drug.
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