Ribozymes with product ejection by strand displacement
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United States of America Patent
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May 20, 1997
Grant Date -
N/A
app pub date -
Apr 22, 1994
filing date -
Apr 22, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Ribozymes designed to provide improved rates of catalytic turnover are described. The compounds of this invention comprise a catalytic region, at least one substrate binding region, and at least one displaceable antisense arm, whereby the rate of release of the endonuclease cleavage fragments is enhanced. A method to make such ribozymes is also described.
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