Process and solvate of 2-methyl-thieno-benzodiazepine
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United States of America Patent
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May 20, 1997
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Mar 24, 1995
filing date -
Mar 24, 1995
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Abstract
The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine (olanzapine) and a process for making such lower alcohol solyates of olanzapine. The invention provides a method for using such solyates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.
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