Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same

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United States of America Patent

PATENT NO 5632981
SERIAL NO

08344157

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Abstract

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A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group; pharmaceutical compositions comprising the polymeric composition; and methods of treating biological disorders in which dosage with nitric oxide is therapeutic.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESOFFICE OF TECHNOLOGY TRANSFER NATIONAL INSTITUTES OF HEALTHBOX OTT BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akamatsu, Miki Rockville, MD 4 209
Keefer, Larry K Bethesda, MD 54 3016
Roller, Peter P Rockville, MD 7 212
Saavedra, Joseph E Thurmont, MD 18 812

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