Process for preparing a porous graft containing endothelial cells
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United States of America Patent
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Jun 3, 1997
Grant Date -
N/A
app pub date -
May 4, 1993
filing date -
May 11, 1992
priority date (Note) -
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Abstract
A process for the production of prostheses wherein endogenic tissue material is substantially mechanically comminuted and, if necessary, additionally enzymatically digested to tissue particles, whose sizes fall within very narrow limits. A preshaped carrier material is treated with the resultant suspension. In the case of a porous carrier material the suspension is filtered through the material, whereas with less or non-porous carrier material the suspension is applied to the material surface by centrifuging. Unlike the case of corresponding prior art processes, as a result of this improvement, the process according to the invention can be performed very rapidly, i.e., directly during the operation and in a closed system.
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