Methods of prevention of oral mucositis with transforming growth factor .beta.
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United States of America Patent
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Jun 3, 1997
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app pub date -
Feb 28, 1995
filing date -
Sep 21, 1992
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Abstract
The present invention provides methods of preventing oral mucositis in a subject susceptible to mucositis which comprises administering to the subject a prophylactically effective amount of TGF-.beta.3. Typically, administration is topical and initiated prior to anti-neoplastic therapy such as radiation treatment or chemotherapy. The invention is particularly suited for pediatric patients.
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