Fiber-optic detectors with terpolymeric analyte-permeable matrix coating
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United States of America Patent
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Jun 17, 1997
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N/A
app pub date -
Mar 27, 1995
filing date -
Mar 27, 1995
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Abstract
The invention provides fiber-optic detectors with rapid response times for measuring analytes in aqueous solutions, including blood. The detectors, because of their size, accuracy, and sterilizability may be used in vitro. In a preferred embodiment, pellets comprising a unique, permeable terpolymer of methyl methacrylate, butyl acrylate and methacrylamidopropyltrimethylammonium chloride; and an indicator for an analyte are used as the detecting element of a fiber-optic sensor. Response times for pH testing are better than 150 seconds at t90%. The pellets are easily made by solvent casting techniques and failure rates are low.
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