Granular drug delivery system
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United States of America Patent
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Jun 24, 1997
Issued Date -
N/A
app pub date -
Sep 13, 1995
filing date -
Nov 10, 1987
priority date (Note) -
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Abstract
A novel granular drug delivery system having a gel-forming dietary fiber that can be made into a an orally-ingestible dispersion by admixture with a liquid that can deliver an effective dose of a pharmaceutically-active compound. The granular drug delivery system comprises granules consisting essentially of a pharmaceutically active compound, and a gel-forming dietary fiber, the granules being coated with at least one of the following: a gel-forming dietary fiber, a starch or a protein. The composition may further include a mineral salt that releases a physiologically-acceptable gas upon ingestion. The composition of the granular drug delivery system will deliver microgram quantities of a pharmaceutically-active compound in an orally-ingestible dispersion without forming a thick gel and without forming 'hot' and 'cold' spots of the pharmaceutically-active compound.
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