Molecular imaging

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United States of America Patent

PATENT NO 5641539
SERIAL NO

08457326

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Abstract

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Disclosed are chemically-produced specific binding, 'molecular imaged' sorbents which reversibly bind a preselected macromolecule by spatially matched multipoint interactions between functional groups synthesized on the surface of the sorbent and functional groups on the surface of the macromolecule. Also disclosed are methods of producing such sorbents. The sorbents typically are high surface area solids comprising surface binding regions which have charged groups, metal coordinating groups, hydrophobic moieties, or various combination thereof anchored thereto and spaced in the mirror image of complementary interactive groups on a surface of the macromolecule.

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Patent Owner(s)

Patent OwnerAddress
APPLIED BIOSYSTEMS LLC5791 VAN ALLEN WAY CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Afeyan, Noubar B Brookline, MA 130 6841
Regnier, Fred West Lafayette, IN 13 614
Varady, Laszlo Malden, MA 7 651

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