System for dispensing pharmaceutically active compounds

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United States of America Patent

PATENT NO 5642728
SERIAL NO

08654006

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method is provided for dispensing a clinically effective dose of an inhalable, pharmaceutically active compound. The method includes providing a dry powder inhaler containing a powder including the pharmaceutically active compound, and administering to a patient a dose of the compound that is less than 70% of the dose that would be necessary to obtain a physiologically equivalent result were the compound administered by a pressurized metered dose inhaler. The pharmaceutically active compound is in the form of primary particles at least 80% of which have a particle size of less than 10 microns, and the primary particles are provided as agglomerates which are deagglomerated during inhalation so that at least 40% of the dose administered is in the form of primary particles.

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Patent Owner(s)

  • ASTRA AKTIEBOLAG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andersson, Jan Sodra Sandby, SE 127 1664
Jagfeldt, Hans Lund, SE 3 277
Trofast, Eva Lund, SE 19 559
Wetterlin, Kjell Sodra Sandby, SE 7 602

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