US Patent No: 5,643,171

Number of patents in Portfolio can not be more than 2000

Method and apparatus for uniform radiation treatment of vascular lumens

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Abstract

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A method and apparatus for intravascular radiotherapy for prevention of stenosis following angioplasty or other trauma to coronary arteries caused by smooth muscle cell hyperplasia in which a uniform dosage of radiation is delivered to the walls of the artery by positively positioning a radioactive source at the radial center of the artery being treated.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BAYLOR COLLEGE OF MEDICINEHOUSTON, TX427
NEOCARDIA, LLCHOUSTON, TX5

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bradshaw, Anthony J Missouri City, TX 21 1111
Raizner, Albert E Houston, TX 6 329

Cited Art Landscape

Patent Info (Count) # Cites Year
 
BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (1)
4,815,449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 184 1987
 
HOOFT, ERIC VAN'T (1)
4,861,520 Capsule for radioactive source 104 1988
 
Medical Innovative Technologies R&D Limited Partnership (1)
5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia 434 1989
 
PROGRESSIVE ANGIOPLASTY SYSTEMS, INC. (1)
5,302,168 Method and apparatus for restenosis treatment 205 1991
 
SYMMETRY MEDICAL USA, INC. (1)
5,295,995 Perfusion dilatation catheter 61 1992
 
WEINSTEIN, JOSEPH S. (1)
5,213,561 Method and devices for preventing restenosis after angioplasty 225 1992
 
Other [Check patent profile for assignment information] (1)
5,308,356 Passive perfusion angioplasty catheter 146 1993

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (26)
5,882,290 Intravascular radiation delivery system 46 1996
6,234,951 Intravascular radiation delivery system 45 1997
5,873,811 Composition containing a radioactive component for treatment of vessel wall 47 1997
6,110,097 Perfusion balloon catheter with radioactive source 21 1997
6,099,454 Perfusion balloon and radioactive wire delivery system 18 1997
6,019,718 Apparatus for intravascular radioactive treatment 31 1997
5,855,546 Perfusion balloon and radioactive wire delivery system 65 1997
5,951,458 Local application of oxidizing agents to prevent restenosis 73 1997
6,264,596 In-situ radioactive medical device 14 1997
6,676,590 Catheter system having tubular radiation source 24 1997
6,059,713 Catheter system having tubular radiation source with movable guide wire 39 1998
6,059,812 Self-expanding medical device for centering radioactive treatment sources in body vessels 67 1998
6,117,065 Perfusion balloon catheter with radioactive source 23 1998
6,413,203 Method and apparatus for positioning radioactive fluids within a body lumen 38 1998
6,398,708 Perfusion balloon and radioactive wire delivery system 39 1998
6,258,019 Catheter for intraluminal treatment of a vessel segment with ionizing radiation 25 1999
6,352,501 Adjustable radiation source 13 1999
6,398,709 Elongated member for intravascular delivery of radiation 36 1999
6,422,989 Method for intravascular radioactive treatment 28 1999
6,267,775 Self-expanding medical device for centering radioactive treatment sources in body vessels 81 2000
6,302,865 Intravascular guidewire with perfusion lumen 0 2000
6,582,353 Intravascular radiation delivery system 21 2000
6,599,230 Intravascular radiation delivery system 4 2001
6,562,031 Guide wire system for RF recanalization of vascular blockages 87 2001
6,488,628 Method for ultrasonically profiling the distribution of an administered medicament 7 2001
7,618,362 Spacer apparatus for radiation and ablation therapy 2 2005
 
ANGIODYNAMICS, INC. (17)
7,063,679 Intra-aortic renal delivery catheter 47 2002
7,481,803 Intra-aortic renal drug delivery catheter 1 2003
7,335,192 Apparatus and methods for treating congestive heart disease 23 2003
7,341,570 Apparatus and methods for treating congestive heart disease 8 2003
7,563,247 Intra-aortic renal delivery catheter 2 2003
7,241,273 Intra-aortic renal delivery catheter 12 2003
7,364,566 Method and apparatus for intra-aortic substance delivery to a branch vessel 15 2005
6,994,700 Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 76 2005
7,585,836 Bi-lateral local renal delivery for treating congestive heart failure and for BNP therapy 2 2005
7,329,236 Intra-aortic renal drug delivery catheter 20 2005
7,993,325 Renal infusion systems and methods 0 2005
7,104,981 Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 22 2005
7,766,961 Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens 5 2005
7,771,401 Selective renal cannulation and infusion systems and methods 2 2007
8,012,121 Method and apparatus for selective material delivery via an intra-renal catheter 3 2007
8,585,678 Method and apparatus for intra-aortic substance delivery to a branch vessel 0 2008
8,518,011 Sheath for use in peripheral interventions 0 2009
 
ENDOLOGIX, INC. (17)
6,699,170 Radiation delivery balloon catheter 43 2000
6,685,618 Method for delivering radiation to an intraluminal site in the body 15 2001
6,953,475 Bifurcation graft deployment catheter 26 2003
8,034,100 Graft deployment system 1 2003
8,147,535 Bifurcation graft deployment catheter 0 2005
8,523,931 Dual concentric guidewire and methods of bifurcated graft deployment 0 2007
8,236,040 Bifurcated graft deployment systems and methods 2 2008
8,221,494 Apparatus and method of placement of a graft or graft system 1 2009
8,216,295 Catheter system and methods of using same 1 2009
8,167,925 Single puncture bifurcation graft deployment system 0 2010
8,491,646 Stent graft 1 2010
8,118,856 Stent graft 1 2010
8,357,192 Bifurcated graft deployment systems and methods 1 2011
8,821,564 Stent graft 0 2012
8,808,350 Catheter system and methods of using same 0 2012
8,672,989 Apparatus and method of placement of a graft or graft system 0 2012
8,764,812 Bifurcated graft deployment systems and methods 0 2013
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (16)
5,910,101 Device for loading and centering a vascular radiation therapy source 72 1996
6,210,312 Catheter and guide wire assembly for delivery of a radiation source 38 1997
5,851,171 Catheter assembly for centering a radiation source within a body lumen 75 1997
5,957,829 Apparatus and method for radiotherapy using a radioactive source wire having a magnetic insert 28 1997
6,224,535 Radiation centering catheters 14 1998
6,159,140 Radiation shielded catheter for delivering a radioactive source and method of use 18 1998
6,142,926 Radiation dose delivery catheter with reinforcing mandrel 20 1998
6,450,988 Centering catheter with improved perfusion 52 1999
7,163,504 Multi-lumen fluted balloon radiation centering catheter 6 2000
6,605,031 Stepped centering balloon for optimal radiation delivery 2 2000
6,582,417 Methods and apparatuses for radiation treatment 50 2000
6,540,734 Multi-lumen extrusion tubing 45 2000
6,527,739 Spiraled balloon arrangement for treatment of a tortuous vessel 28 2000
6,645,135 Intravascular catheter device and method for simultaneous local delivery of radiation and a therapeutic substance 162 2001
7,090,635 Methods and apparatuses for radiation treatment 0 2003
7,994,449 Square-wave laser bonding 0 2005
 
VARIAN MEDICAL SYSTEMS, INC. (9)
6,129,658 Method and apparatus creating a radioactive layer on a receiving substrate for in vivo implantation 30 1997
6,360,116 Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-operative planning and post-operative evaluations 71 1999
6,327,490 Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-implantation planning and post-implantation evaluations with storage of multiple plan variations for a single patient 39 1999
6,352,500 Neutron brachytherapy device and method 6 1999
6,817,995 Reinforced catheter connector and system 11 2000
6,497,645 Remote afterloader 6 2000
6,770,021 Neutron brachytherapy device and method 1 2001
6,685,619 Methods for treating solid tumors using neutron therapy 15 2001
6,539,247 BRACHYTHERAPY SYSTEM FOR PROSTATE CANCER TREATMENT WITH COMPUTER IMPLEMENTED SYSTEMS AND PROCESSES TO FACILITATE PRE-IMPLANTATION PLANNING AND POST-IMPLANTATION EVALUATIONS WITH STORAGE OF MULTIPLE PLAN VARIATIONS FOR A SINGLE PATIENT 45 2001
 
Schneider (Europe) A.G. (7)
6,074,338 Medical appliances for the treatment of blood vessels by means of ionizing radiation 32 1994
5,728,042 Medical appliance for ionizing radiation treatment having radiopaque markers 75 1995
6,146,322 Irradiating filament and method of making same 31 1996
6,231,494 Medical device with radiation source 26 1997
6,616,629 Medical appliance with centering balloon 11 1999
6,514,191 Medical appliances for the treatment of blood vessels by means of ionizing radiation 16 2000
6,582,352 Medical appliance for treatment by ionizing radiation 2 2001
 
Radiance Medical Systems, Inc. (6)
6,048,299 Radiation delivery catheter 51 1997
6,149,574 Dual catheter radiation delivery system 98 1998
6,176,821 Radiation delivery balloon catheter 37 1998
6,287,249 Thin film radiation source 67 1999
6,261,320 Radioactive vascular liner 97 1999
6,491,619 Radiation delivery catheters and dosimetry methods 27 2000
 
BEST VASCULAR, INC. (5)
7,160,238 Method and apparatus for treating a desired area in the vascular system of a patient 2 1999
6,503,185 Method and apparatus for treating a desired area in the vascular system of a patient 52 1999
7,066,872 Method and apparatus for treating a desired area in the vascular system of a patient 2 2003
7,066,873 Automated system for the radiation treatment of a desired area within the body of a patient 4 2003
6,994,665 Method and apparatus for treating a desired area in the vascular system of a patient 1 2004
 
INTERVENTIONAL THERAPIES, LLC (5)
5,947,924 Dilatation/centering catheter used for the treatment of stenosis or other constriction in a bodily passageway and method thereof 48 1996
6,770,058 Treatment catheter insert 25 1997
6,442,822 Flexible source wire for localized internal irradiation of tissue 11 1998
6,234,952 Dilatation/centering catheter used for the treatment of stenosis or other construction in a bodily passageway and method thereof 14 1999
6,629,920 Energy filtering system 1 2001
 
MEDTRONIC AVE, INC. (5)
6,273,850 Device for positioning a radiation source at a stenosis treatment site 38 1997
6,496,561 Devices, methods and systems for delivery of X-ray 17 1998
6,074,339 Expandable braid device and method for radiation treatment 38 1998
6,196,963 Brachytherapy device assembly and method of use 46 1999
6,679,860 Intraluminal therapy catheter with inflatable helical member and methods of use 11 2001
 
MEDTRONIC, INC. (4)
5,938,582 Radiation delivery centering catheter 83 1997
6,099,499 Device for in vivo radiation delivery and method for delivery 31 1998
6,117,386 Centering perfusion delivery catheter and method of manufacture 13 1998
6,093,142 Device for in vivo radiation delivery and method for delivery 34 1998
 
XOFT, INC. (4)
6,390,967 Radiation for inhibiting hyperplasia after intravascular intervention 85 2000
7,041,046 Combination ionizing radiation and immunomodulator delivery devices and methods for inhibiting hyperplasia 3 2001
7,018,371 Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia 12 2001
6,537,195 Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia 26 2001
 
COAPTUS MEDICAL CORPORATION (3)
8,052,677 Transseptal left atrial access and septal closure 0 2004
7,257,450 Systems and methods for securing cardiovascular tissue 27 2004
8,235,986 Systems and methods for transeptal cardiac procedures, including tissue penetrating members and associated methods 0 2008
 
CORDIS CORPORATION (3)
5,891,091 Irradiation catheter and method of use 56 1996
5,863,285 Balloon catheter with radioactive means 73 1997
7,306,617 Spiral centering catheter 3 2004
 
PORTOLA MEDICAL, INC. (3)
8,137,256 Brachytherapy apparatus 0 2005
7,862,497 Brachytherapy device having seed tubes with individually-settable tissue spacings 0 2007
8,226,539 Brachytherapy apparatus for asymmetrical body cavities 0 2009
 
SALUTARIS MEDICAL DEVICES, INC. (3)
8,430,804 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 1 2009
8,608,632 Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye 0 2011
8,597,169 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 0 2013
 
VOLCANO THERAPEUTICS, INC. (3)
6,024,690 Radiation source with delivery wire 52 1997
6,077,213 Intravascular radiation delivery device 23 1998
6,309,339 Intravascular radiation delivery device 8 1998
 
GENZYME CORPORATION (2)
6,352,682 Polymeric delivery of radionuclides and radiopharmaceuticals 20 1997
5,942,209 Method of local radiotherapy by polymerizing a material in vivo to form a hydrogel 182 1997
 
PERCUSURGE, INC. (2)
6,338,709 Intravascular radiation therapy device and method of use 62 1998
6,312,407 Occlusion of a vessel 133 1998
 
ACOUS TX CORPORATION (1)
8,021,359 Transseptal closure of a patent foramen ovale and other cardiac defects 3 2004
 
Angio Dynamics (1)
7,914,503 Method and apparatus for selective material delivery via an intra-renal catheter 1 2005
 
CARDIOVASCULAR DYNAMICS, INC. (1)
5,782,742 Radiation delivery balloon 113 1997
 
COOK MEDICAL TECHNOLOGIES LLC (1)
8,403,977 Self-orienting delivery system 1 2007
 
DELFT INSTRUMENTS INTELLECTUAL PROPERTY B.V. (1)
6,068,611 Catheter having centering means 14 1999
 
EMORY UNIVERSITY (1)
6,273,858 Systems and methods for providing radiation therapy and catheter guides 35 2000
 
Endology, INC. (1)
6,458,069 Multi layer radiation delivery balloon 66 1999
 
ENDOSONICS CORPORATION (1)
6,033,357 Intravascular radiation delivery device 85 1997
 
FLOWMEDICAINC. (1)
7,780,628 Apparatus and methods for treating congestive heart disease 8 2000
 
FLOWMEDICAL INC. (1)
6,749,598 Apparatus and methods for treating congestive heart disease 74 1999
 
GANZ, ROBERT A. (1)
6,095,966 X-ray device having a dilation structure for delivering localized radiation to an interior of a body 81 1998
 
GMP/VASCULAR, INC. (1)
6,409,651 Device for intravascular delivery of beta emitting isotopes 19 2000
 
INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (1)
6,213,976 Brachytherapy guide catheter 57 1999
 
INNOVATIVE HEARTH PRODUCTS, INC. (1)
6,416,457 System and method for intravascular ionizing tandem radiation therapy 19 2000
 
LIBRA (1)
7,122,019 Intra-aortic renal drug delivery catheter 61 2000
 
MEDTRONIC VASCULAR, INC. (1)
6,994,689 Occlusion of a vessel 19 2000
 
NUCLETRON OPERATIONS B.V. (1)
6,572,633 Catheter 0 1999
 
OREGON HEALTH & SCIENCE UNIVERSITY (1)
7,909,862 Delivery systems and methods for deploying expandable intraluminal medical devices 1 2004
 
Polymerex Medical Corp. (1)
6,508,784 Balloon catheter having adjustable centering capabilities and methods thereof 55 2000
 
RADIOVASCULAR SYSTEMS, L.L.C. (1)
6,475,644 Radioactive coating solutions methods, and substrates 14 1999
 
SALUTARIS MEDICAL DEVIES, INC. (1)
7,273,445 Intraocular brachytherapy device and method 24 2004
 
SCIMED LIFE SYSTEMS, INC. (1)
6,203,485 Low attenuation guide wire for intravascular radiation delivery 46 1999
 
The Trustees of Columbia University in the City of New York (1)
6,605,030 Apparatus and method for treating a disease process in a luminal structure 21 1998
 
United States Surgical Corporation (1)
5,833,593 Flexible source wire for localized internal irradiation of tissue 98 1995
 
UNIVERSITY OF IOWA RESEARCH FOUNDATION (1)
6,607,476 Brachytherapy positioning system 25 1999
 
VARIAN ASSOCIATES, INC. (1)
6,626,815 Method and apparatus creating a radioactive layer on a receiving substrate for in vivo implantation 0 1999
 
VOLCANO CORPORATION (1)
6,387,035 Catheter with swivel tip 27 1999
 
ZOLL CIRCULATION, INC. (1)
8,753,302 Indwelling heat exchange catheter and method of using same 0 2013
 
Other [Check patent profile for assignment information] (2)
6,187,037 Metal stent containing radioactivatable isotope and method of making same 52 1998
6,585,715 Irradiation catheter and method of use 2 2000