US Patent No: 5,643,171

Number of patents in Portfolio can not be more than 2000

Method and apparatus for uniform radiation treatment of vascular lumens

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method and apparatus for intravascular radiotherapy for prevention of stenosis following angioplasty or other trauma to coronary arteries caused by smooth muscle cell hyperplasia in which a uniform dosage of radiation is delivered to the walls of the artery by positively positioning a radioactive source at the radial center of the artery being treated.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
BAYLOR COLLEGE OF MEDICINEHOUSTON, TX247
NEOCARDIA, LLCHOUSTON, TX5

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bradshaw, Anthony J Missouri City, TX 21 1280
Raizner, Albert E Houston, TX 6 349

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 5,308,356 Passive perfusion angioplasty catheter 173 1993
 
BRUCE S. HOROWITZ, 494 N.W. 165TH STREET, APT. #C302, MIAMI, FLORIDA 33167 (1)
* 4,815,449 Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member 185 1987
 
PROGRESSIVE ANGIOPLASTY SYSTEMS, INC. (1)
* 5,302,168 Method and apparatus for restenosis treatment 213 1991
 
Medical Innovative Technologies R&D Limited Partnership (1)
* 5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia 457 1989
 
WEINSTEIN, JOSEPH S. (1)
* 5,213,561 Method and devices for preventing restenosis after angioplasty 227 1992
 
SYMMETRY MEDICAL USA, INC. (1)
* 5,295,995 Perfusion dilatation catheter 68 1992
 
HOOFT, ERIC VAN'T (1)
* 4,861,520 Capsule for radioactive source 108 1988
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (5)
6,187,037 Metal stent containing radioactivatable isotope and method of making same 56 1998
6,585,715 Irradiation catheter and method of use 4 2000
* 2003/0199,848 Methods and apparatuses for radiation treatment 5 2003
* 2010/0121,346 Compliant Guiding Catheter Sheath System 0 2010
* 2013/0296,985 INDWELLING HEAT EXCHANGE CATHETER AND METHOD OF USING SAME 0 2013
 
DELFT INSTRUMENTS INTELLECTUAL PROPERTY B.V. (1)
* 6,068,611 Catheter having centering means 17 1999
 
SCIMED LIFE SYSTEMS, INC. (1)
6,203,485 Low attenuation guide wire for intravascular radiation delivery 58 1999
 
PORTOLA MEDICAL, INC. (4)
8,137,256 Brachytherapy apparatus 3 2005
* 2007/0142,694 Brachytherapy apparatus 18 2005
7,862,497 Brachytherapy device having seed tubes with individually-settable tissue spacings 0 2007
8,226,539 Brachytherapy apparatus for asymmetrical body cavities 1 2009
 
The Trustees of Columbia University in the City of New York (1)
* 6,605,030 Apparatus and method for treating a disease process in a luminal structure 26 1998
 
INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (1)
6,213,976 Brachytherapy guide catheter 71 1999
 
LIBRA (1)
7,122,019 Intra-aortic renal drug delivery catheter 140 2000
 
Angio Dynamics (1)
7,914,503 Method and apparatus for selective material delivery via an intra-renal catheter 5 2005
 
VOLCANO CORPORATION (1)
6,387,035 Catheter with swivel tip 28 1999
 
VOLCANO THERAPEUTICS, INC. (3)
* 6,024,690 Radiation source with delivery wire 52 1997
* 6,077,213 Intravascular radiation delivery device 23 1998
6,309,339 Intravascular radiation delivery device 9 1998
 
CORDIS CORPORATION (4)
* 5,891,091 Irradiation catheter and method of use 60 1996
* 5,863,285 Balloon catheter with radioactive means 76 1997
* 7,306,617 Spiral centering catheter 8 2004
* 2005/0171,592 Spiral centering catheter 9 2004
 
COAPTUS MEDICAL CORPORATION (5)
8,052,677 Transseptal left atrial access and septal closure 0 2004
7,257,450 Systems and methods for securing cardiovascular tissue 32 2004
8,235,986 Systems and methods for transeptal cardiac procedures, including tissue penetrating members and associated methods 1 2008
* 2009/0118,726 Systems and Methods for Transeptal Cardiac Procedures, Including Tissue Sealing Members Associated Methods 45 2008
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UNIVERSITY OF IOWA RESEARCH FOUNDATION (1)
* 6,607,476 Brachytherapy positioning system 29 1999
 
GENZYME CORPORATION (2)
6,352,682 Polymeric delivery of radionuclides and radiopharmaceuticals 22 1997
* 5,942,209 Method of local radiotherapy by polymerizing a material in vivo to form a hydrogel 213 1997
 
ACOUS TX CORPORATION (1)
8,021,359 Transseptal closure of a patent foramen ovale and other cardiac defects 12 2004
 
CARDIOVASCULAR DYNAMICS, INC. (1)
* 5,782,742 Radiation delivery balloon 118 1997
 
EMORY UNIVERSITY (1)
6,273,858 Systems and methods for providing radiation therapy and catheter guides 56 2000
 
Cardiac Pacemakers, Inc. (1)
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INTERVENTIONAL THERAPIES, LLC (5)
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6,770,058 Treatment catheter insert 28 1997
* 6,442,822 Flexible source wire for localized internal irradiation of tissue 11 1998
6,234,952 Dilatation/centering catheter used for the treatment of stenosis or other construction in a bodily passageway and method thereof 18 1999
6,629,920 Energy filtering system 1 2001
 
MEDTRONIC VASCULAR, INC. (1)
6,994,689 Occlusion of a vessel 33 2000
 
NUCLETRON OPERATIONS B.V. (1)
6,572,633 Catheter 1 1999
 
FLOWMEDICAL INC. (1)
6,749,598 Apparatus and methods for treating congestive heart disease 113 1999
 
FLOWMEDICAINC. (1)
7,780,628 Apparatus and methods for treating congestive heart disease 20 2000
 
ACOUSTX CORPORATION (2)
* 2007/0142,699 Methods and implantable apparatuses for treating an esophageal disorder such as gastroesophageal reflux disease 0 2005
* 2007/0142,884 Methods and apparatuses for treating an esophageal disorder such as gastroesophageal reflux disease 1 2005
 
OREGON HEALTH & SCIENCE UNIVERSITY (2)
7,909,862 Delivery systems and methods for deploying expandable intraluminal medical devices 2 2004
* 2004/0225,322 Delivery systems and methods for deploying expandable intraluminal medical devices 95 2004
 
Advanced Cardiovascular Systems, Inc. (16)
* 5,910,101 Device for loading and centering a vascular radiation therapy source 82 1996
6,210,312 Catheter and guide wire assembly for delivery of a radiation source 40 1997
* 5,851,171 Catheter assembly for centering a radiation source within a body lumen 78 1997
* 5,957,829 Apparatus and method for radiotherapy using a radioactive source wire having a magnetic insert 28 1997
6,224,535 Radiation centering catheters 14 1998
* 6,159,140 Radiation shielded catheter for delivering a radioactive source and method of use 18 1998
* 6,142,926 Radiation dose delivery catheter with reinforcing mandrel 21 1998
6,450,988 Centering catheter with improved perfusion 77 1999
7,163,504 Multi-lumen fluted balloon radiation centering catheter 7 2000
* 6,605,031 Stepped centering balloon for optimal radiation delivery 2 2000
6,582,417 Methods and apparatuses for radiation treatment 53 2000
6,540,734 Multi-lumen extrusion tubing 66 2000
6,527,739 Spiraled balloon arrangement for treatment of a tortuous vessel 49 2000
* 6,645,135 Intravascular catheter device and method for simultaneous local delivery of radiation and a therapeutic substance 188 2001
7,090,635 Methods and apparatuses for radiation treatment 0 2003
7,994,449 Square-wave laser bonding 0 2005
 
POLYMEREX MEDICAL CORP. (1)
6,508,784 Balloon catheter having adjustable centering capabilities and methods thereof 71 2000
 
BEST VASCULAR, INC. (7)
7,160,238 Method and apparatus for treating a desired area in the vascular system of a patient 2 1999
6,503,185 Method and apparatus for treating a desired area in the vascular system of a patient 86 1999
* 7,066,872 Method and apparatus for treating a desired area in the vascular system of a patient 2 2003
* 2003/0229,259 Method and apparatus for treating a desired area in the vascular system of a patient 2 2003
* 7,066,873 Automated system for the radiation treatment of a desired area within the body of a patient 7 2003
6,994,665 Method and apparatus for treating a desired area in the vascular system of a patient 1 2004
* 2004/0192,999 Method and apparatus for treating a desired area in the vascular system of a patient 1 2004
 
RADIOVASCULAR SYSTEMS, L.L.C. (1)
6,475,644 Radioactive coating solutions methods, and substrates 15 1999
 
MEDTRONIC, INC. (4)
* 5,938,582 Radiation delivery centering catheter 88 1997
* 6,099,499 Device for in vivo radiation delivery and method for delivery 32 1998
* 6,117,386 Centering perfusion delivery catheter and method of manufacture 13 1998
* 6,093,142 Device for in vivo radiation delivery and method for delivery 37 1998
 
VARIAN MEDICAL SYSTEMS, INC. (9)
* 6,129,658 Method and apparatus creating a radioactive layer on a receiving substrate for in vivo implantation 31 1997
6,360,116 Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-operative planning and post-operative evaluations 83 1999
6,327,490 Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-implantation planning and post-implantation evaluations with storage of multiple plan variations for a single patient 39 1999
6,352,500 Neutron brachytherapy device and method 6 1999
6,817,995 Reinforced catheter connector and system 16 2000
6,497,645 Remote afterloader 6 2000
6,770,021 Neutron brachytherapy device and method 1 2001
6,685,619 Methods for treating solid tumors using neutron therapy 17 2001
6,539,247 BRACHYTHERAPY SYSTEM FOR PROSTATE CANCER TREATMENT WITH COMPUTER IMPLEMENTED SYSTEMS AND PROCESSES TO FACILITATE PRE-IMPLANTATION PLANNING AND POST-IMPLANTATION EVALUATIONS WITH STORAGE OF MULTIPLE PLAN VARIATIONS FOR A SINGLE PATIENT 46 2001
 
MEDTRONIC AVE, INC. (6)
6,273,850 Device for positioning a radiation source at a stenosis treatment site 39 1997
6,496,561 Devices, methods and systems for delivery of X-ray 19 1998
* 6,074,339 Expandable braid device and method for radiation treatment 51 1998
6,196,963 Brachytherapy device assembly and method of use 57 1999
6,679,860 Intraluminal therapy catheter with inflatable helical member and methods of use 21 2001
* 2002/0198,432 Brachytherapy catheter with twisted lumens and methods of use 2 2001
 
COOK MEDICAL TECHNOLOGIES LLC (1)
8,403,977 Self-orienting delivery system 2 2007
 
RADIANCE MEDICAL SYSTEMS, INC. (6)
* 6,048,299 Radiation delivery catheter 85 1997
* 6,149,574 Dual catheter radiation delivery system 101 1998
6,176,821 Radiation delivery balloon catheter 43 1998
6,287,249 Thin film radiation source 71 1999
6,261,320 Radioactive vascular liner 108 1999
6,491,619 Radiation delivery catheters and dosimetry methods 31 2000
 
VARIAN ASSOCIATES, INC. (1)
6,626,815 Method and apparatus creating a radioactive layer on a receiving substrate for in vivo implantation 0 1999
 
XOFT, INC. (5)
6,390,967 Radiation for inhibiting hyperplasia after intravascular intervention 101 2000
7,041,046 Combination ionizing radiation and immunomodulator delivery devices and methods for inhibiting hyperplasia 4 2001
7,018,371 Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia 15 2001
6,537,195 Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia 40 2001
* 2005/0124,844 Combination ionizing radiation and radiosensitizer delivery devices and methods for inhibiting hyperplasia 2 2004
 
PERCUSURGE, INC. (2)
6,338,709 Intravascular radiation therapy device and method of use 75 1998
6,312,407 Occlusion of a vessel 153 1998
 
ANGIODYNAMICS, INC. (23)
7,063,679 Intra-aortic renal delivery catheter 134 2002
7,481,803 Intra-aortic renal drug delivery catheter 54 2003
7,335,192 Apparatus and methods for treating congestive heart disease 88 2003
* 2004/0064,091 Apparatus and methods for treating congestive heart disease 56 2003
7,341,570 Apparatus and methods for treating congestive heart disease 59 2003
* 2004/0097,900 Apparatus and methods for treating congestive heart disease 5 2003
7,563,247 Intra-aortic renal delivery catheter 43 2003
7,241,273 Intra-aortic renal delivery catheter 54 2003
7,364,566 Method and apparatus for intra-aortic substance delivery to a branch vessel 62 2005
6,994,700 Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 121 2005
* 2005/0245,882 Method and apparatus for intra-aortic substance delivery to a branch vessel 55 2005
* 2005/0245,892 Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 56 2005
7,585,836 Bi-lateral local renal delivery for treating congestive heart failure and for BNP therapy 2 2005
7,329,236 Intra-aortic renal drug delivery catheter 81 2005
* 2006/0189,960 Intra-aortic renal drug delivery catheter 58 2005
* 2006/0069,323 Systems and methods for bi-lateral guidewire cannulation of branched body lumens 81 2005
7,993,325 Renal infusion systems and methods 1 2005
7,104,981 Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 32 2005
7,766,961 Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens 24 2005
7,771,401 Selective renal cannulation and infusion systems and methods 6 2007
8,012,121 Method and apparatus for selective material delivery via an intra-renal catheter 7 2007
8,585,678 Method and apparatus for intra-aortic substance delivery to a branch vessel 0 2008
8,518,011 Sheath for use in peripheral interventions 2 2009
 
Schneider (Europe) A.G. (7)
6,074,338 Medical appliances for the treatment of blood vessels by means of ionizing radiation 33 1994
* 5,728,042 Medical appliance for ionizing radiation treatment having radiopaque markers 78 1995
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6,231,494 Medical device with radiation source 26 1997
6,616,629 Medical appliance with centering balloon 17 1999
6,514,191 Medical appliances for the treatment of blood vessels by means of ionizing radiation 18 2000
6,582,352 Medical appliance for treatment by ionizing radiation 2 2001
 
GMP/VASCULAR, INC. (1)
6,409,651 Device for intravascular delivery of beta emitting isotopes 19 2000
 
Endology, INC. (1)
6,458,069 Multi layer radiation delivery balloon 76 1999
 
ENDOLOGIX, INC. (21)
6,699,170 Radiation delivery balloon catheter 51 2000
6,685,618 Method for delivering radiation to an intraluminal site in the body 19 2001
6,953,475 Bifurcation graft deployment catheter 30 2003
8,034,100 Graft deployment system 2 2003
8,147,535 Bifurcation graft deployment catheter 0 2005
8,523,931 Dual concentric guidewire and methods of bifurcated graft deployment 0 2007
8,236,040 Bifurcated graft deployment systems and methods 4 2008
* 2009/0105,806 STENT 9 2008
8,221,494 Apparatus and method of placement of a graft or graft system 6 2009
8,216,295 Catheter system and methods of using same 3 2009
8,167,925 Single puncture bifurcation graft deployment system 0 2010
8,945,202 Fenestrated prosthesis 0 2010
8,491,646 Stent graft 2 2010
8,118,856 Stent graft 2 2010
8,357,192 Bifurcated graft deployment systems and methods 2 2011
9,393,100 Devices and methods to treat vascular dissections 0 2011
8,821,564 Stent graft 1 2012
8,808,350 Catheter system and methods of using same 0 2012
8,672,989 Apparatus and method of placement of a graft or graft system 1 2012
8,764,812 Bifurcated graft deployment systems and methods 0 2013
9,149,381 Apparatus and method of placement of a graft or graft system 0 2014
 
INNOVATIVE HEARTH PRODUCTS, INC. (1)
6,416,457 System and method for intravascular ionizing tandem radiation therapy 24 2000
 
ZOLL CIRCULATION, INC. (2)
* 8,753,302 Indwelling heat exchange catheter and method of using same 0 2013
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SALUTARIS MEDICAL DEVIES, INC. (2)
7,273,445 Intraocular brachytherapy device and method 25 2004
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8,430,804 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 2 2009
8,608,632 Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye 0 2011
8,597,169 Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye 0 2013
 
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* 5,882,290 Intravascular radiation delivery system 48 1996
6,234,951 Intravascular radiation delivery system 49 1997
* 5,873,811 Composition containing a radioactive component for treatment of vessel wall 56 1997
* 6,110,097 Perfusion balloon catheter with radioactive source 22 1997
* 6,099,454 Perfusion balloon and radioactive wire delivery system 23 1997
* 6,019,718 Apparatus for intravascular radioactive treatment 31 1997
* 5,855,546 Perfusion balloon and radioactive wire delivery system 70 1997
* 5,951,458 Local application of oxidizing agents to prevent restenosis 78 1997
6,264,596 In-situ radioactive medical device 14 1997
6,676,590 Catheter system having tubular radiation source 25 1997
* 6,059,713 Catheter system having tubular radiation source with movable guide wire 39 1998
* 6,059,812 Self-expanding medical device for centering radioactive treatment sources in body vessels 76 1998
* 6,117,065 Perfusion balloon catheter with radioactive source 30 1998
6,413,203 Method and apparatus for positioning radioactive fluids within a body lumen 43 1998
6,398,708 Perfusion balloon and radioactive wire delivery system 61 1998
6,258,019 Catheter for intraluminal treatment of a vessel segment with ionizing radiation 27 1999
6,352,501 Adjustable radiation source 14 1999
6,398,709 Elongated member for intravascular delivery of radiation 36 1999
6,422,989 Method for intravascular radioactive treatment 34 1999
* 6,267,775 Self-expanding medical device for centering radioactive treatment sources in body vessels 108 2000
6,302,865 Intravascular guidewire with perfusion lumen 1 2000
6,582,353 Intravascular radiation delivery system 26 2000
6,599,230 Intravascular radiation delivery system 6 2001
6,562,031 Guide wire system for RF recanalization of vascular blockages 137 2001
6,488,628 Method for ultrasonically profiling the distribution of an administered medicament 10 2001
7,618,362 Spacer apparatus for radiation and ablation therapy 2 2005
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GANZ, ROBERT A. (1)
6,095,966 X-ray device having a dilation structure for delivering localized radiation to an interior of a body 92 1998
 
ENDOSONICS CORPORATION (1)
* 6,033,357 Intravascular radiation delivery device 97 1997
 
United States Surgical Corporation (1)
* 5,833,593 Flexible source wire for localized internal irradiation of tissue 137 1995
* Cited By Examiner