US Patent No: 5,643,246

Number of patents in Portfolio can not be more than 2000

Electromagnetically triggered, responsive gel based drug delivery device

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Abstract

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A system for remotely inducing a phase transition in a gel is provided. The system includes a gel capable of volume change in response to an environmental stimulus, a seed material in contact with the gel, and generating a time-varying magnetic or a time-varying electric or electromagnetic field in the proximity of the gel to produce the environmental stimulus. In a preferred embodiment, the environmental stimulus is temperature.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDLOGIC GLOBAL LIMITEDCHESHIRE36

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hovorka, George Boston, MA 24 269
Leeb, Steven B Belmont, MA 35 533
Lupton, E C Boston, MA 8 157
Yu, Xiaohong Boston, MA 19 282

Cited Art Landscape

Patent Info (Count) # Cites Year
 
LA CORPORATION DE L'ECOLE POLYTECHNIQUE (1)
* 5,366,454 Implantable medication dispensing device 66 1993
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
* 4,657,543 Ultrasonically modulated polymeric devices for delivering compositions 77 1984
 
Other [Check patent profile for assignment information] (2)
* 4,545,368 Induction heating method for use in causing necrosis of neoplasm 90 1983
* 4,767,611 Method for affecting intracellular and extracellular electric and magnetic dipoles 30 1984
 
CHILDREN'S MEDICAL CENTER CORPORATION (1)
* 5,019,372 Magnetically modulated polymeric drug release system 130 1990
 
SUN WAN KIM (1)
* 5,226,902 Pulsatile drug delivery device using stimuli sensitive hydrogel 59 1991
 
GORDON, DAVID, SKOKIE, ILLINOIS (2)
* 4,662,359 Use of magnetic susceptibility probes in the treatment of cancer 45 1983
* 4,735,796 Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease 82 1985
 
ADVANCED MAGNETICS, INC. (1)
* 4,827,945 Biologically degradable superparamagnetic materials for use in clinical applications 86 1987
 
SENJU PHARMACEUTICAL CO., LTD. (1)
* 5,152,758 Electroresponsive hydrogel and physiologically active substance release control system 68 1990
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
9,042,965 Biopsy marker with in situ-generated imaging properties 0 2013
9,039,763 Tissue marking implant 0 2014
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (3)
8,216,259 Compositions and methods for joining non-conjoined lumens 1 2007
8,608,760 Compositions and methods for joining non-conjoined lumens 0 2007
8,197,499 Compositions and methods for joining non-conjoined lumens 1 2008
 
VASCULAR CONTROL SYSTEMS, INC. (1)
7,983,734 Fibrous marker and intracorporeal delivery thereof 9 2003
 
THE INVENTION SCIENCE FUND I, LLC (25)
8,998,884 Remote controlled in situ reaction method 0 2005
8,617,141 Remote controlled in situ reaction device 0 2005
8,585,684 Reaction device controlled by magnetic control signal 0 2005
7,817,030 Remote controller for in situ reaction device 9 2005
9,028,467 Osmotic pump with remotely controlled osmotic pressure generation 0 2005
8,998,886 Remote control of osmotic pump device 0 2005
8,273,075 Osmotic pump with remotely controlled osmotic flow rate 8 2005
7,699,834 Method and system for control of osmotic pump device 24 2005
8,882,747 Substance delivery system 0 2006
7,942,867 Remotely controlled substance delivery device 8 2006
8,992,511 Acoustically controlled substance delivery device 0 2006
8,936,590 Acoustically controlled reaction device 0 2006
8,529,551 Acoustically controlled substance delivery device 8 2006
8,568,388 Remote controlled in situ reaction device 0 2006
8,109,923 Osmotic pump with remotely controlled osmotic pressure generation 8 2006
7,819,858 Remote controlled in vivo reaction method 8 2006
8,968,274 Acoustically controlled substance delivery device 0 2008
8,083,710 Acoustically controlled substance delivery device 9 2008
8,192,390 Method and system for control of osmotic pump device 8 2008
7,896,868 Method and system for control of osmotic pump device 8 2008
8,367,003 Acoustically controlled reaction device 8 2009
8,349,261 Acoustically controlled reaction device 8 2009
8,273,071 Remote controller for substance delivery system 0 2009
8,172,833 Remote control of substance delivery system 0 2009
8,114,065 Remote control of substance delivery system 8 2009
 
C.R. BARD, INC. (8)
8,401,622 Biopsy marker with in situ-generated imaging properties 4 2007
8,670,818 Marker delivery device for tissue marker placement 0 2008
8,311,610 Biopsy tissue marker 4 2009
8,437,834 Breast marker 5 2011
D716450 Tissue marker for intracorporeal site identification 0 2013
D716451 Tissue marker for intracorporeal site identification 0 2013
D715942 Tissue marker for intracorporeal site identification 0 2013
D715442 Tissue marker for intracorporeal site identification 0 2013
 
DAKO DENMARK A/S (1)
* 6,930,292 Method of controlling the temperature of a specimen in or on a solid support member 18 2000
 
DEVICOR MEDICAL PRODUCTS, INC. (1)
8,292,822 Biopsy localization method and device 0 2004
 
FOSTER-MILLER, INC. (1)
8,158,002 Responsive gels and methods of use thereof 0 2000
 
BATTELLE MEMORIAL INSTITUTE (2)
6,979,464 Reversible geling co-polymer and method of making 9 1998
7,033,571 Multiple stimulus reversible hydrogels 25 2003
 
BARD PERIPHERAL VASCULAR, INC. (2)
8,579,931 Apparatus for the percutaneous marking of a lesion 8 2011
8,486,028 Tissue marking apparatus having drug-eluting tissue marker 5 2011
 
BARD SHANNON LIMITED (1)
8,634,899 Multi mode imaging marker 0 2006
 
The United States of America as represented by the Secretary of the Navy (1)
* 6,143,138 Visible light pH change for activating polymers and other pH dependent reactants 6 1998
 
EUROPEAN INSTITUTE OF SCIENCE AB (1)
* 6,739,342 Device for therapeutic purposes on human tissue, for influencing injected magnetic particles with an alternating electro-magnetic gradient field 16 2002
 
TAUTONA GROUP LP (2)
8,172,861 Compositions and methods for joining non-conjoined lumens 0 2008
8,563,037 Compositions and methods for joining non-conjoined lumens 0 2009
 
SENORX, INC. (42)
* 6,161,034 Methods and chemical preparations for time-limited marking of biopsy sites 182 1999
6,427,081 Methods and chemical preparations for time-limited marking of biopsy sites 56 2000
6,497,706 Biopsy device and method of use 25 2000
6,725,083 Tissue site markers for in VIVO imaging 74 2000
6,638,234 Sentinel node location and biopsy 59 2000
6,540,695 Biopsy anchor device with cutter 53 2000
6,679,851 Tissue accessing and anchoring device and method 48 2001
6,662,041 Imageable biopsy site marker 49 2001
7,377,902 Biopsy anchor device with cutter 7 2002
6,716,179 Sentinel node location and biopsy 26 2002
6,567,689 Methods and chemical preparations for time-limited marking of biopsy sites 55 2002
6,862,470 Cavity-filling biopsy site markers 52 2002
6,875,182 Electrosurgical specimen-collection system 1 2002
7,651,505 Plugged tip delivery for marker placement 31 2002
6,758,848 Apparatus and method for accessing a body site 16 2002
7,877,133 Marker or filler forming fluid 17 2003
7,047,063 Tissue site markers for in vivo imaging 62 2003
6,996,433 Imageable biopsy site marker 47 2003
7,282,034 Tissue accessing and anchoring device and method 1 2003
6,993,375 Tissue site markers for in vivo imaging 51 2004
7,229,439 Apparatus and method for accessing a body site 5 2004
7,792,569 Cavity-filling biopsy site markers 7 2004
7,565,191 Tissue site markers for in vivo imaging 12 2005
8,147,487 Apparatus and method for accessing a body site 0 2007
8,360,990 Biopsy device with aperture orientation and improved tip 0 2007
8,343,071 Biopsy device with aperture orientation and improved tip 0 2007
7,970,454 Marker delivery device with releasable plug 0 2008
8,224,424 Tissue site markers for in vivo imaging 0 2009
8,177,792 Plugged tip delivery tube for marker placement 0 2009
8,718,745 Tissue site markers for in vivo imaging 0 2010
8,219,182 Cavity-filling biopsy site markers 0 2010
8,157,862 Tissue marking implant 9 2010
8,447,386 Marker or filler forming fluid 0 2010
8,361,082 Marker delivery device with releasable plug 8 2011
8,498,693 Intracorporeal marker and marker delivery device 0 2011
8,626,269 Fibrous marker and intracorporeal delivery thereof 6 2011
8,668,737 Tissue marking implant 1 2012
8,784,433 Plugged tip delivery tube for marker placement 0 2012
8,626,270 Cavity-filling biopsy site markers 7 2012
8,639,315 Marker or filler forming fluid 5 2013
8,880,154 Fibrous marker and intracorporeal delivery thereof 0 2013
8,965,486 Cavity filling biopsy site markers 0 2013
* Cited By Examiner