US Patent No: 5,643,246

Number of patents in Portfolio can not be more than 2000

Electromagnetically triggered, responsive gel based drug delivery device

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Abstract

A system for remotely inducing a phase transition in a gel is provided. The system includes a gel capable of volume change in response to an environmental stimulus, a seed material in contact with the gel, and generating a time-varying magnetic or a time-varying electric or electromagnetic field in the proximity of the gel to produce the environmental stimulus. In a preferred embodiment, the environmental stimulus is temperature.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDLOGIC GLOBAL LIMITEDCHESHIRE53

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hovorka, George Boston, MA 15 181
Leeb, Steven B Belmont, MA 23 312
Lupton, E C Boston, MA 8 116
Yu, Xiaohong Boston, MA 17 192

Cited Art

Patent Info (Count) # Cites Year
 
GORDON, DAVID, SKOKIE, ILLINOIS (2)
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4,735,796 Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease 78 1985
 
ADVANCED MAGNETICS, INC. (1)
4,827,945 Biologically degradable superparamagnetic materials for use in clinical applications 76 1987
 
CHILDREN'S MEDICAL CENTER CORPORATION (1)
5,019,372 Magnetically modulated polymeric drug release system 76 1990
 
LA CORPORATION DE L'ECOLE POLYTECHNIQUE (1)
5,366,454 Implantable medication dispensing device 65 1993
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
4,657,543 Ultrasonically modulated polymeric devices for delivering compositions 64 1984
 
SENJU PHARMACEUTICAL CO., LTD. (1)
5,152,758 Electroresponsive hydrogel and physiologically active substance release control system 63 1990
 
SUN WAN KIM (1)
5,226,902 Pulsatile drug delivery device using stimuli sensitive hydrogel 47 1991
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (2)
4,545,368 Induction heating method for use in causing necrosis of neoplasm 86 1983
4,767,611 Method for affecting intracellular and extracellular electric and magnetic dipoles 29 1984

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
SENORX, INC. (32)
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6,427,081 Methods and chemical preparations for time-limited marking of biopsy sites 33 2000
6,497,706 Biopsy device and method of use 16 2000
6,725,083 Tissue site markers for in VIVO imaging 38 2000
6,638,234 Sentinel node location and biopsy 29 2000
6,540,695 Biopsy anchor device with cutter 39 2000
6,679,851 Tissue accessing and anchoring device and method 30 2001
6,662,041 Imageable biopsy site marker 26 2001
7,377,902 Biopsy anchor device with cutter 1 2002
6,716,179 Sentinel node location and biopsy 17 2002
6,567,689 Methods and chemical preparations for time-limited marking of biopsy sites 28 2002
6,862,470 Cavity-filling biopsy site markers 28 2002
6,875,182 Electrosurgical specimen-collection system 0 2002
7,651,505 Plugged tip delivery for marker placement 7 2002
6,758,848 Apparatus and method for accessing a body site 10 2002
7,877,133 Marker or filler forming fluid 3 2003
7,047,063 Tissue site markers for in vivo imaging 33 2003
6,996,433 Imageable biopsy site marker 22 2003
7,282,034 Tissue accessing and anchoring device and method 0 2003
6,993,375 Tissue site markers for in vivo imaging 25 2004
7,229,439 Apparatus and method for accessing a body site 0 2004
7,792,569 Cavity-filling biopsy site markers 0 2004
7,565,191 Tissue site markers for in vivo imaging 0 2005
8,147,487 Apparatus and method for accessing a body site 0 2007
8,360,990 Biopsy device with aperture orientation and improved tip 0 2007
8,343,071 Biopsy device with aperture orientation and improved tip 0 2007
7,970,454 Marker delivery device with releasable plug 0 2008
8,224,424 Tissue site markers for in vivo imaging 0 2009
8,177,792 Plugged tip delivery tube for marker placement 0 2009
8,219,182 Cavity-filling biopsy site markers 0 2010
8,157,862 Tissue marking implant 0 2010
8,361,082 Marker delivery device with releasable plug 0 2011
 
THE INVENTION SCIENCE FUND I, LLC (14)
7,817,030 Remote controller for in situ reaction device 0 2005
8,273,075 Osmotic pump with remotely controlled osmotic flow rate 0 2005
7,699,834 Method and system for control of osmotic pump device 11 2005
7,942,867 Remotely controlled substance delivery device 0 2006
8,109,923 Osmotic pump with remotely controlled osmotic pressure generation 0 2006
7,819,858 Remote controlled in vivo reaction method 0 2006
8,083,710 Acoustically controlled substance delivery device 0 2008
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C.R. BARD, INC. (3)
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6,979,464 Reversible geling co-polymer and method of making 7 1998
7,033,571 Multiple stimulus reversible hydrogels 16 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (2)
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DAKO DENMARK A/S (1)
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8,292,822 Biopsy localization method and device 0 2004
 
EUROPEAN INSTITUTE OF SCIENCE AB (1)
6,739,342 Device for therapeutic purposes on human tissue, for influencing injected magnetic particles with an alternating electro-magnetic gradient field 2 2002
 
FOSTER-MILLER, INC. (1)
8,158,002 Responsive gels and methods of use thereof 0 2000
 
TAUTONA GROUP, L.P. (1)
8,172,861 Compositions and methods for joining non-conjoined lumens 0 2008
 
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (1)
6,143,138 Visible light pH change for activating polymers and other pH dependent reactants 4 1998
 
VASCULAR CONTROL SYSTEMS, INC. (1)
7,983,734 Fibrous marker and intracorporeal delivery thereof 1 2003