Microbial process for preparation of indolopyrrolocarbazole derivatives
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United States of America Patent
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Jul 1, 1997
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Jun 7, 1995
filing date -
Nov 29, 1991
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Abstract
Indolopyrrolocarbazole derivatives, such as, for example, 12,13-dihydro-1,11-dihydroxy-13-(.beta.-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(6H)-dione or 6-amino derivative thereof, are produced by glycosylating a precursor compound by cultivating with Microtetraspora sp. A34549, Saccharothrix aerocolonigenes ATCC 39243 or mutants thereof, in a nutrient medium containing the precursor compound.
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