Prevention of calcification and degeneration of biological tissue grafts for implantation in humans
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United States of America Patent
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Jul 8, 1997
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N/A
app pub date -
Jun 5, 1996
filing date -
Jun 5, 1996
priority date (Note) -
Expired
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Abstract
The present invention relates to chemical treatment for prevention of calcification and degeneration of biological tissue grafts used as a whole or in a part as heart valve substitutes, substitutes of blood vessel, pericardial substitutes, and surgical membranes for implantation in human. The process includes the steps of treatment of the grafts with partially degraded heparin to prevent the calcification of glutaraldehyde-treated xenografts.
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