Use of hydrogels to fix bone replacements

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United States of America Patent

PATENT NO 5645592
SERIAL NO

08341541

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Abstract

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Provided are orthopedic fasteners and replacements such as nails, screws, pins, hip and knee replacements, etc., coated with hydrogels and other biocompatible/biodegradable materials which expand in the presence of liquids. Swelling of such coatings causes the fastener or replacement to be securely fixed into position once inserted into bone material. Useful coating materials include methacrylates, hyaluronic acid esters, and crosslinked esters of hyaluronic acid resulting from the esterification of hyaluronic acid with polyhydric alcohols. Also provided is a method for fixing a bone or bone replacement in position employing such coated orthopedic fasteners or replacements.

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Patent Owner(s)

  • M.U.R.S.T. (ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH);M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ambrosio, Luigi Ottaviano, IT 16 244
Callegaro, Lanfranco Ponte di Brenta, IT 69 1322
Netti, Paolo Antonio S. Gennaro Vesuviano, IT 3 103
Nicolais, Luigi Ercolano, IT 26 202

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