Inhibitor resistant serine proteases
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United States of America Patent
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Jul 8, 1997
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N/A
app pub date -
Feb 3, 1995
filing date -
Aug 4, 1992
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Abstract
Serine proteases of the chymotrypsin superfamily are modified so that they exhibit resistance to serine protease inhibitors. If such modified serine proteases have fibrinolytic, thrombolytic, antithrombotic or prothrombotic properties, they are useful in the treatment of blood clotting diseases or conditions.
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