Selective acylation of epsilon-amino groups
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United States of America Patent
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Jul 8, 1997
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app pub date -
Nov 17, 1994
filing date -
Nov 17, 1994
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Abstract
The present invention relates to the acylation of proteins. More particularly, the invention relates to a one-step process for selectively acylating the free .epsilon.-amino group of insulin, insulin analog, or proinsulin in the presence of a free .alpha.-amino group.
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