Nucleozymes

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United States of America Patent

PATENT NO 5652094
SERIAL NO

07829729

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY A CORP OF MASSACHUSETTSCAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cedergren, Robert J Montreal, CA 6 96
Perreault, Jean-Pierre Rawdon, CA 9 97
Rich, Alexander Cambridge, MA 41 955
Usman, Nassim Boston, MA 82 3245
Yang, Jing-Hua Montreal, CA 4 54

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