Physiologically active substance well capable of permeating biomembrane
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United States of America Patent
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Jul 29, 1997
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N/A
app pub date -
Apr 15, 1994
filing date -
Feb 28, 1990
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Expired
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Abstract
A physiologically active substance well capable of permeating biomembrane according to the present invention is represented by: ##STR1## where R represents a residue of a physiologically active substance comprising a peptide, amino acid, aliphatic amine having a phenol skeleton, amino sugar, nucleoside or lactam compound and a residue of physiologically active derivative thereof. The biomembrane permeability of a substance with poor biomembrane permeability can be improved by introducing an adamantyl group to the physiologically active substance.
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