Oral transmucosal delivery tablet and method of making it
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United States of America Patent
Stats
-
Aug 12, 1997
Grant Date -
N/A
app pub date -
Apr 24, 1995
filing date -
Apr 24, 1995
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A tablet for delivering a pharmaceutical to a human transmucosally is described. The excipient is a gel which is elastic enough for a comfortable fit in the mouth, has suitable gel strength, holds a suitable amount of pharmaceutical and has a structure which allows at least bi-directional delivery of the pharmaceutical to opposed oral mucosa. The tablet is placed between the upper lip mucosa and the opposite gingiva mucosa, and is held in place without any adhesive, by virtue of a snug fit and the elasticity of the tablet. The tablet is made from an organic polymer, e.g., agarose, and water, glycerol and a pharmaceutical, which may be any of a wide range of pharmaceuticals.
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