Heterodimeric receptor libraries using phagemids

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United States of America Patent

PATENT NO 5658727
SERIAL NO

08133011

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Abstract

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Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a filamentous phage coat protein membrane anchor domain fused to at least one of the polypeptides.

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Patent Owner(s)

  • THE SCRIPPS RESEARCH INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbas, Carlos La Jolla, CA 5 658
Kang, Angray Carlsbad, CA 6 611
Lerner, Richard A La Jolla, CA 114 2643

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