CDNA encoding a novel human protein tyrosine phosphatase
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United States of America Patent
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Aug 19, 1997
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N/A
app pub date -
Dec 1, 1994
filing date -
Sep 14, 1993
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Abstract
A novel human protein tyrosine phosphatase (PTP) has been identified and its cDNA has been isolated. This novel PTP, denoted PTP-OB, has a receptor-like three dimensional structure and is present in osteoblasts. PTP-OB is involved in osteoblast differentiation, and modulators of PTP-OB activity in turn modulate osteoblast differentiation, osteoclast differentiation and osteoclast activity.
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