Method and compounds for aica riboside delivery and for lowering blood glucose
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United States of America Patent
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Aug 19, 1997
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N/A
app pub date -
Dec 14, 1994
filing date -
Jan 24, 1989
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Abstract
AICA riboside and prodrugs of AICA riboside are provided which lower blood glucose for the treatment of various pathologic conditions, including hypoglycemia, insulin deficiency, insulin resistance diabetes and Syndrome X. Prodrugs of AICA riboside provide AICA riboside in an orally bioavailable form. The use of adenosine kinase inhibition and ZMP enhancement for lowering blood glucose are also described.
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