US Patent No: 5,660,993
Number of patents in Portfolio can not be more than 2000
Disposable device in diagnostic assays
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Aug 26, 1997
Issued date -
Aug 24, 1994
filing date -
08/296,489
serial no -
Expired
status
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Abstract
A disposable diagnostic assay device and method for its use are provided. The device comprises a sample addition port in fluid communication with at least one main channel. The main channel comprises, in the direction of fluid flow, a main reagent area in fluid communication with an incubation area and a waste area. In fluid communication with the main channel is at least one side reagent channel. The side reagent channels comprise, in the direction of fluid flow, a liquid addition port and a side reagent area in fluid communication with the main channel at a region of the main channel upstream from the incubation area. Agitation means may be included in the at least one of the main and side reagent areas and/or the incubation area. Capillary valves may be located at various positions along the main and side reagent channels upstream from the incubation area, providing for control over fluid flow through the device. Applications in which the device finds use include diagnostic assays employing signal producing systems based on the interactions of specific binding pair members, where optical signals are related to the presence of analyte.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
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| 4,963,498 Capillary flow device | 460 | 1988 | |
| 5,223,219 Analytical cartridge and system for detecting analytes in liquid samples | 104 | 1992 | |
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| 5,198,368 Methods for performing a solid-phase immunoassay | 16 | 1991 | |
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| 4,855,240 Solid phase assay employing capillary flow | 150 | 1987 | |
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| 5,217,905 Device and method for the rapid qualitative and quantitative determination of the presence of a reactive ligand in a fluid | 25 | 1988 | |
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| 4,426,451 Multi-zoned reaction vessel having pressure-actuatable control means between zones | 321 | 1981 | |
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| 4,918,025 Self contained immunoassay element | 65 | 1987 | |
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| 5,207,988 Apparatus for detecting and quantifying clot lysis and establishing optimum medication and dosages | 32 | 1989 | |
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| 4,859,421 Disposable antigen concentrator and detector | 20 | 1987 | |
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| 5,399,486 Disposable unit in diagnostic assays | 37 | 1993 | |