Modified lambda bacteriophage
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United States of America Patent
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Sep 2, 1997
Issued Date -
N/A
app pub date -
Dec 8, 1995
filing date -
Apr 27, 1993
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Disclosed is a protein construct including a chemically modified lambdoid tail protein having a chemically reactive amino acid residue linked to a target molecule. Also disclosed is an infective lambdoid bacteriophage displaying on its outer surface the chemically modified tail protein. In addition, methods of detecting a molecule-of-interest in a solution and methods of detecting cells producing a molecule-of-interest which utilize the infective lambdoid bacteriophage having the chemically modified tail protein are disclosed.
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