Hypolipidaemic benzothiazepine compounds

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United States of America Patent

PATENT NO 5663165
SERIAL NO

08290805

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to the following compounds of formula (I): ##STR1## wherein l is an integer of from 0 to 4; m is an integer of from 0 to 5; n is an integer of from 0 to 2; R and R' are atoms or groups independently selected from halogen, nitro, phenylalkoxy, C.sub.1-4 alkoxy, C.sub.1-6 alkyl and --O(CH.sub.2).sub.p SO.sub.3 R' wherein p is an integer of from 1 to 4 and R' is hydrogen or C.sub.1-6 alkyl, wherein said phenylalkoxy, alkoxy and alkyl groups are optionally substituted by one or more halogen atoms; R.sup.4 is a C.sub.1-6 straight alkyl group; and R.sup.5 is a C.sub.2-6 straight alkyl group; and their salts, solvates and physiologically functional derivatives, with processes and novel intermediates for their preparation, with pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidaemic conditions, such as atherosclerosis.

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Patent Owner(s)

Patent OwnerAddress
BURROUGHS WELLCOME COA CORP OF NC RESEARCH TRIANGLE PARK NC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brieaddy, Lawrence Edward Raleigh, NC 6 290

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