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Abstract

A pocket-type apparatus for non-invasive measurement of blood glucose concentration based on producing a polarized-modulated laser beam via an optical phase shifter (32), measuring a phase difference introduced, e.g., by a finger (F) or a ear lobule (E) of a subject, measuring phase difference between a reference signal (SR) and a measurement signal (SM), and processing the obtained data which are then presented as blood glucose concentration. The optical phase shifter (32) comprises a pair of fiber-optic arms (40 and 42). The laser beam is fed to one of the fiber-optic arms (4) then both arms are guided through an input optical coupler (44) which splits the laser beam into a first component, which further propagates through the first optic-fiber arm (40), and a second component, which propagates through second optic-fiber arm (42). An optical phase shifter (48) which is attached to the first fiber-optic arm (40) modulates the first component of the laser beam. Both arms are then guided through an output optical coupler (46) which coherently mixes the light-propagating modes of the fiber-optic arms so that the output of each arm has a complementary coherent mixture of the beam first and second components with an orthogonal direction of polarization. An output of one of the fiber-optic arms is used as a reference optical signal and an output of the other fiber-optic arm is used as a measuring optical signal.

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