Amorphous paroxetine composition
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United States of America Patent
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Sep 30, 1997
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N/A
app pub date -
Sep 9, 1996
filing date -
Sep 9, 1996
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Expired
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Abstract
A free-flowing, amorphous paroxetine hydrochloride-ethanol composition suitable as a therapeutic agent for premature ejaculation can be prepared by dissolving paroxetine free base in a hydrochloric acid-ethanol solution followed by drying. In a preferred embodiment, the amount of ethanol present in the amorphous product is in the range of 1 to 4 weight percent based on paroxetine hydrochloride. The amorphous product is stable and substantially non-hygroscopic.
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