Aerosol formulations containing P134a and salbutamol

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United States of America Patent

PATENT NO 5674471
SERIAL NO

08444725

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a pharmaceutical aerosol formulation consisting essentially of particulate medicament which is salbutamol or a physiologically acceptable salt or solvate thereof and 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% surfactant based upon the weight of medicament, particulate medicament being present in an amount of 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns, with the provisos that when said formulation consists of salbutamol and 1,1,1,2-tetrafluoroethane in a weight ratio of 0.05:18, said salbutamol is present in the form of a physiologically acceptable salt and when said formulation consists of salbutamol or salbutamol sulphate and 1,1,1,2-tetrafluoroethane the weight to weight ratio of medicament to propellant is other than 69:7900 or 0.866%.

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Patent Owner(s)

Patent OwnerAddress
GLAXO GROUP LIMITEDGLAXO WELLCOME HOUSE BERKELEY AVENUE GREENFORD MIDDLESEX UB6 0NN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akehurst, Rachel Ann Ware, GB3 29 994
Taylor, Anthony James Ware, GB3 44 1392
Wyatt, David Andrew Ware, GB3 29 994

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