DNA encoding thermostable nucleic acid polymerase enzyme from thermus species Z05

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United States of America Patent

PATENT NO 5674738
SERIAL NO

08520422

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Abstract

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A purified thermostable enzyme is derived from the eubacterium Thermus species Z05. The enzyme has DNA polymerase, activity reverse transcriptase activity, and optionally 5'.fwdarw.3' exonuclease activity. The enzyme can be native or recombinant, and may be used with primers and nucleoside triphosphates in a temperature-cycling chain reaction where at least one nucleic acid sequence is amplified in quantity from an existing sequence.

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Patent Owner(s)

Patent OwnerAddress
ROCHE MOLECULAR SYSTEMS INC4300 HACIENDA DRIVE PLEASANTON CA 94588

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abramson, Richard D Oakland, CA 5 358
Gelfand, David H Oakland, CA 57 7373
Greenfield, I Lawrence Pleasant Hill, CA 19 440

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