Antiinfective polyoxypropylene/polyoxyethylene copolymers and methods of use
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United States of America Patent
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Oct 7, 1997
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N/A
app pub date -
Jun 6, 1995
filing date -
Feb 20, 1987
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Expired
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Abstract
The present invention comprises novel preparations of polyoxypropylene/polyoxyethylene copolymers which retain the therapeutic activity of the commercial preparations, but substantially reduce the undesirable effects which are inherent in the prior art preparations. Because the preparations of polyoxypropylene/polyoxyethylene copolymers which comprise the present invention are a less polydisperse population of molecules than the prior art polyoxypropylene/polyoxyethylene copolymers, the biological activity of the copolymers is better defined and more predictable and the cardiotoxicity inherent in the native copolymers is substantially reduced.
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