US Patent No: 5,677,355

Number of patents in Portfolio can not be more than 2000

Continuous open-cell polymeric foams containing living cells

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Abstract

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A polymeric foam with continuous, open-cell pores containing living cells suitable for medical applications and methods for preparing these foams. The microporous foams are of controlled pore size that may be utilized in a variety of applications. In general, the foams are characterized in that the pores are continuous and open-celled. In preparing the foams, an organic polymer is melted and combined with a selected solid crystalline fugitive compound, that melts above about 25.degree. C. and/or that sublimates at above about 25.degree. C. or can be extracted, to produce a substantially isotropic solution. The solution is cooled under controlled conditions to produce a foam precursor containing the solidified fugitive composition dispersed through a matrix of the organic polymer. Crystals of fugitive composition are then removed by solvent extraction and/or sublimation, or a like process to produce microcellular foams having a continuous, open-cell structure. After removing the fugitive composition, living cells capable of producing biologically active products are added to the pores to produce a foam containing living cells.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
POLY-MED, INC.ANDERSON, SC100
SMITH & NEPHEW, INC.MEMPHIS, TN689

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Roweton, Susan L Clemson, SC 7 225
Shalaby, Shalaby W Anderson, SC 224 4320

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
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Patent Citation Ranking

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