Oligonucleotide analogues containing phosphate diester linkage substitutes, compositions thereof, and precursor dinucleotide analogues
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United States of America Patent
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Oct 14, 1997
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N/A
app pub date -
May 24, 1995
filing date -
Aug 3, 1990
priority date (Note) -
Expired
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Abstract
The present invention relates to compounds, compositions and methods for inhibiting gene expression. The compounds of this invention comprise 1) oligonucleoside sequences of from about 6 to about 200 bases having a three atom internucleoside linkage or 2) oligonucleotide sequences of from about 9 to about 200 bases having a diol at either or both termini.
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