Process for simultaneously removing tumour necrosis factor .alpha. and bacterial lipopolysaccharides from an aqueous liquid
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United States of America Patent
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Oct 21, 1997
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N/A
app pub date -
Sep 26, 1995
filing date -
Oct 5, 1994
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Abstract
Disclosed is a process to remove tumour necrosis factor .alpha. (TNF.alpha.) or/and bacterial lipopolysaccharides (LPS) from an aqueous liquid, in particular blood, blood plasma or serum, in an extracorporeal perfusion system after removing corpuscular blood components if necessary, wherein (a) the pH value of the body fluid is adjusted to pH<6, (b) a precipitation reagent in the form of a polyanion is added, (c) precipitated substances are removed by filtration or/and centrifugation and (d) the resulting liquid is passed over an anion exchanger.
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