Percutaneous absorption preparation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5683710
SERIAL NO

08527535

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Abstract

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A percutaneous absorption preparation for use in the administration of isosorbide dinitrate (ISDN) as a coronary vasodilator into the living body by percutaneous absorption, which has excellent adhesion to the skin and does not cause pain and damage to stratum corneum when peeled off, is disclosed. The pressure-sensitive adhesive layer comprises an acrylic copolymer prepared by copolymerization of a monomer mixture comprising a (meth)acrylic acid alkyl ester and a functional monomer as the essential components, a fatty acid ester having a specified number of carbon atoms, a monoglyceride having a specified number of carbon atoms, and ISDN, and the pressure-sensitive adhesive layer is crosslinked. Since its skin adhesive property is improved by the inclusion of the monoglyceride, release of ISDN is improved and the area of the preparation can be decreased.

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Patent Owner(s)

Patent OwnerAddress
NITTO DENKO CORPORATIONIBARAKI-SHI OSAKA 567-8680
TOA EIYO LTDTOKYO JAPAN TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akemi, Hitoshi Osaka, JP 35 420
Higashio, Kazuhiro Osaka, JP 11 258
Kinoshita, Takashi Osaka, JP 125 1110
Muraoka, Takateru Osaka, JP 13 244
Otsuka, Saburo Osaka, JP 25 677

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