Methods and compositions for combinatorial-based discovery of new multimeric molecules

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United States of America Patent

PATENT NO 5683899
SERIAL NO

08678462

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Abstract

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The present invention prowdes methods and compositions for producing and screening combinatorial libraries of multimeric proteins. The present invention relies on the use of filamentous fungal heterokaryons that are produced using two or more parent strains into which a population of DNA molecules encoding variants of a multimeric protein have been introduced.

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Patent Owner(s)

Patent OwnerAddress
HAWAII UNIVERSITY OF2425 CAMPUS ROAD SINCLAIR 10 HONOLULU HI 96822

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Stuart, W Dorsey Kaneche, HI 9 289

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