Determination of oligonucleotides for therapeutics, diagnostics and research reagents

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United States of America Patent

PATENT NO 5686242
SERIAL NO

08330000

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Abstract

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Oligonucleotides which selectively bind to target biomolecules are determined by in vitro assay of a pool of random oligonucleotides for activity against said biomolecules, followed by recovery and characterization of selected oligonucleotides. Oligonucleotides so determined may be utilized for therapeutic, diagnostic and research reagent purposes.

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Patent Owner(s)

  • ISIS PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bruice, Thomas W Carlsbad, CA 16 812
Lima, Walter F San Diego, CA 30 707

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