Assay method for the detection of 26kd TNF prohormone

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United States of America Patent

PATENT NO 5686259
SERIAL NO

08463894

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Abstract

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Cleavage site blocking antibody that binds to prohormones, preferable Tumor Necrosis Factor, thereby preventing the formation of prohormone fragment(s) by proteolysis of the prohormone, and uses of the antibody including prophylactic and therapeutic methods to treat disease, and diagnostic assays for determining the amount of the prohormone and prohormone fragments present in a patients body.

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Patent Owner(s)

Patent OwnerAddress
CHIRON CORPORATION4650 HORTON STREET EMERYVILLE CALIFORNIA 94608 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kriegler, Michael San Francisco, CA 21 241
Perez, Carl Berkeley, CA 19 165

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