Domains of extracellular region of human platelet derived growth factor receptor polypeptides

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United States of America Patent

PATENT NO 5686572
SERIAL NO

08168917

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Abstract

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Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.

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Patent Owner(s)

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COR THERAPEUTICS INCCALIFORNIA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Escobedo, Jaime A San Francisco, CA 16 128
Fretto, Larry J Belmont, CA 9 194
Giese, Neill A San Francisco, CA 18 369
Tomlinson, James E San Francisco, CA 29 144
Williams, Lewis Thomas Tiburon, CA 17 169
Wolf, David Palo Alto, CA 99 2014

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