Composition and method for tumor imaging
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United States of America Patent
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Nov 18, 1997
Grant Date -
N/A
app pub date -
May 16, 1995
filing date -
Apr 3, 1989
priority date (Note) -
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Abstract
A method is provided for enhancing transmembrane transport of a diagnostic agent across a membrane of a living cell. The method comprises contacting a membrane of a living cell with a complex formed between said diagnostic agent and ligands selected from biotin or biotin receptor-binding analogs of biotin, folate or folate receptor-binding analogs of folate, riboflavin or riboflavin receptor-binding analogs of riboflavin to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for imaging tissues in vivo.
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